{
  "_id": "6aca63e6fe5cc25786e884f2",
  "Package": "dfcomb",
  "Type": "Package",
  "Title": "Phase I/II Adaptive Dose-Finding Design for Combination Studies",
  "Version": "3.1-5",
  "Date": "2026-03-02",
  "Authors@R": "c(person(given = \"Marie-Karelle\",\nfamily = \"Riviere\",\nrole = \"aut\"),\nperson(given = \"Jacques-Henri\",\nfamily = \"Jourdan\",\nrole = c(\"aut\", \"cre\"),\nemail = \"jacques-henri.jourdan@cnrs.fr\"))",
  "Copyright": "src/arms.c and src/arms.h are copyright Wally Gilks. All\nother files are copyright Sanofi-Aventis R&D, Institut de\nRecherches Internationales Servier and Institut national de la\nsante et de la recherche medicale.",
  "Description": "Phase I/II adaptive dose-finding design for combination\nstudies where toxicity rates are supposed to increase with both\nagents.",
  "License": "GPL-3",
  "NeedsCompilation": "yes",
  "Packaged": {
    "Date": "2026-10-10 15:14:14 UTC",
    "User": "root"
  },
  "Author": "Marie-Karelle Riviere [aut], Jacques-Henri Jourdan [aut, cre]",
  "Maintainer": "Jacques-Henri Jourdan <jacques-henri.jourdan@cnrs.fr>",
  "Repository": "https://jhjourdan.r-universe.dev",
  "Date/Publication": "2026-03-02 11:50:03 UTC",
  "RemoteUrl": "https://github.com/cran/dfcomb",
  "RemoteRef": "HEAD",
  "RemoteSha": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
  "_user": "jhjourdan",
  "_type": "src",
  "_file": "dfcomb_3.1-5.tar.gz",
  "_fileid": "https://r2.ropensci.org/58f6de2f06655dff34c0ed613ba790c39424ef685c11519983a86ee1723a49be",
  "_filesize": 134948,
  "_sha256": "58f6de2f06655dff34c0ed613ba790c39424ef685c11519983a86ee1723a49be",
  "_expires": "2027-01-18T16:12:21.000Z",
  "_created": "2026-10-10T15:14:14.000Z",
  "_published": "2026-10-10T16:12:22.719Z",
  "_buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_jobs": [
    {
      "job": 114244345393,
      "time": 91,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11673678002"
    },
    {
      "job": 114244345396,
      "time": 104,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11673428431"
    },
    {
      "job": 114244345348,
      "time": 87,
      "config": "linux-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11673059279"
    },
    {
      "job": 114244345442,
      "time": 106,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11673074184"
    },
    {
      "job": 114244345382,
      "time": 69,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11674704220"
    },
    {
      "job": 114244345352,
      "time": 395,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11674225708"
    },
    {
      "job": 114244345335,
      "time": 106,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11675154059"
    },
    {
      "job": 114244345364,
      "time": 354,
      "config": "macos-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11674460442"
    },
    {
      "job": 114243816814,
      "time": 160,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11673014119"
    },
    {
      "job": 114244345317,
      "time": 97,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "11673119189"
    },
    {
      "job": 114244345467,
      "time": 336,
      "config": "windows-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11673523694"
    },
    {
      "job": 114244345499,
      "time": 150,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11673608168"
    },
    {
      "job": 114244345507,
      "time": 136,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11673653124"
    },
    {
      "job": 114244345479,
      "time": 330,
      "config": "windows-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11673688493"
    },
    {
      "job": 114244345456,
      "time": 98,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11673024305"
    }
  ],
  "_upstream": "https://github.com/cran/dfcomb",
  "_commit": {
    "id": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
    "author": "Jacques-Henri Jourdan <jacques-henri.jourdan@cnrs.fr>",
    "committer": "cran-robot <csardi.gabor+cran@gmail.com>",
    "message": "version 3.1-5\n",
    "time": 1772452203
  },
  "_maintainer": {
    "name": "Jacques-Henri Jourdan",
    "email": "jacques-henri.jourdan@cnrs.fr",
    "login": "jhjourdan",
    "description": "",
    "uuid": 1917144
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.2.3",
      "role": "Depends"
    },
    {
      "package": "BH",
      "version": ">= 1.55",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "RcppProgress",
      "version": ">= 0.2.1",
      "role": "LinkingTo"
    }
  ],
  "_owner": "cran",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2026-10",
      "n": 1
    }
  ],
  "_tags": [
    {
      "name": "3.1-5",
      "date": "2026-03-02"
    }
  ],
  "_stars": 1,
  "_contributors": [
    {
      "user": "marie-karelle",
      "count": 12,
      "uuid": 11962644
    },
    {
      "user": "jhjourdan",
      "count": 7,
      "uuid": 1917144
    }
  ],
  "_userbio": {
    "uuid": 1917144,
    "type": "user",
    "name": "Jacques-Henri Jourdan",
    "followers": 54
  },
  "_downloads": {
    "count": 423,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/dfcomb"
  },
  "_searchresults": 4,
  "_topics": [
    "cpp"
  ],
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/dfcomb.html",
    "extra/manual.pdf"
  ],
  "_realowner": "jhjourdan",
  "_cranurl": false,
  "_releases": [
    {
      "version": "1.0",
      "date": "2014-11-06"
    },
    {
      "version": "1.0-1",
      "date": "2014-11-07"
    },
    {
      "version": "2.0-2",
      "date": "2015-01-24"
    },
    {
      "version": "2.1",
      "date": "2015-04-21"
    },
    {
      "version": "2.1-1",
      "date": "2015-04-26"
    },
    {
      "version": "2.1-3",
      "date": "2015-04-29"
    },
    {
      "version": "2.1-4",
      "date": "2015-09-11"
    },
    {
      "version": "2.1-5",
      "date": "2015-10-05"
    },
    {
      "version": "2.1-6",
      "date": "2016-06-21"
    },
    {
      "version": "2.2",
      "date": "2017-03-27"
    },
    {
      "version": "2.3",
      "date": "2017-05-22"
    },
    {
      "version": "2.4",
      "date": "2018-01-07"
    },
    {
      "version": "2.4-2",
      "date": "2018-01-10"
    },
    {
      "version": "2.5-0",
      "date": "2018-05-24"
    },
    {
      "version": "2.6-0",
      "date": "2019-02-22"
    },
    {
      "version": "3.0-0",
      "date": "2019-03-19"
    },
    {
      "version": "3.1-1",
      "date": "2023-01-07"
    },
    {
      "version": "3.1-4",
      "date": "2024-09-30"
    },
    {
      "version": "3.1-5",
      "date": "2026-03-02"
    }
  ],
  "_exports": [
    "CombIncrease_next",
    "CombIncrease_sim"
  ],
  "_help": [
    {
      "page": "dfcomb-package",
      "title": "Phase I/II Adaptive Dose-Finding Design for Combination Studies",
      "topics": [
        "dfcomb-package",
        "dfcomb"
      ]
    },
    {
      "page": "CombIncrease_next",
      "title": "Combination determination with logistic model",
      "topics": [
        "CombIncrease_next",
        "print.CombIncrease_next"
      ]
    },
    {
      "page": "CombIncrease_sim",
      "title": "Combination design Simulator using Logistic model",
      "topics": [
        "CombIncrease_sim",
        "print.CombIncrease_sim"
      ]
    }
  ],
  "_rundeps": [
    "BH",
    "Rcpp",
    "RcppProgress"
  ],
  "_sysdeps": [
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "16-20260322-1ubuntu1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    }
  ],
  "_score": 1,
  "_indexed": true,
  "_nocasepkg": "dfcomb",
  "_universes": [
    "jhjourdan"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "3.1-5",
      "date": "2026-10-10T15:15:56.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/a041d18ac65df4bca2d785768d7778ede90a642b137e7983d8eb1adbc76ee404",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "3.1-5",
      "date": "2026-10-10T15:16:06.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/eeb3e5b4a3e898244490e6d81af7c0f0f680bddec6d462f1d965aa347d3b4761",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "3.1-5",
      "date": "2026-10-10T15:15:54.000Z",
      "distro": "resolute",
      "arch": "aarch64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/5c3360da7548ee52ac829fd7834367aab50258361be41a569414cd32d58bbb45",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "3.1-5",
      "date": "2026-10-10T15:16:08.000Z",
      "distro": "resolute",
      "arch": "x86_64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/68d07e31d85017d797641275c7d6e44aa6db8842d324efc908ebd73f2e85f188",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "3.1-5",
      "date": "2026-10-10T16:06:36.000Z",
      "arch": "aarch64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/6b403823a6870a5023cd85f698bca866010da3f7d430c123e245589e4e785fcf",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "3.1-5",
      "date": "2026-10-10T15:32:30.000Z",
      "arch": "x86_64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/bf7bcf0aa809682a9411d00d112f0dc2c78b937dc0a3f3f84693a09f671fc804",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "3.1-5",
      "date": "2026-10-10T16:11:42.000Z",
      "arch": "aarch64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/426f16996ae263bd31450891e5125195066316a79995d7917b5dae7ce0fa792b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "3.1-5",
      "date": "2026-10-10T15:32:35.000Z",
      "arch": "x86_64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/eb153ffd6ee9bcdd41b75c98832df97e7501593abcc07128a9fbc515c4e84a60",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "3.1-5",
      "date": "2026-10-10T15:16:09.000Z",
      "arch": "emscripten",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/0c60afd10b085400562c95bbf4095e3d96423ee26365a620ae8594bdf4f67dc3",
      "status": "success",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "3.1-5",
      "date": "2026-10-10T15:19:16.000Z",
      "arch": "aarch64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/8cfbf937ee64dff3cac4ea2f80b9a52b403d8663ec213f9d8aa3445b6fb1e455",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "3.1-5",
      "date": "2026-10-10T15:16:05.000Z",
      "arch": "x86_64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/937e651a8c46f8bdd0e352b022a700a696f4dcc9a8fe26f64e3781bd14772af7",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "3.1-5",
      "date": "2026-10-10T15:15:43.000Z",
      "arch": "x86_64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/782323e78ce5056c8401bf820c431a2e496778d8fbc1197f1bdd6100ccb871ed",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "3.1-5",
      "date": "2026-10-10T15:19:20.000Z",
      "arch": "aarch64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/28283f5d14e4b933cdbdaf4247e1671fd6fc0a09ab923f8fccb32df5bc425dd1",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "3.1-5",
      "date": "2026-10-10T15:15:37.000Z",
      "arch": "x86_64",
      "commit": "969d09f3a26cf6ba64f75efba90e634864d02dc6",
      "fileid": "https://r2.ropensci.org/100f96c58fabb506d2877149f6f3f87c274425fc94aa6ede618d7ef2c713a8e3",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/jhjourdan/actions/runs/38062610136"
    }
  ]
}